Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.59 |
| ▸ | WNT3A | P56704 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186990 | 0.96 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5969827 | 0.88 | HDAC6 (0.51) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5946 | 0.84 | RAB9A (0.71) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL5777206 | 0.82 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL31321875 | 0.82 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL31025406 | 0.82 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| Hydrochloric Acid SCHEMBL2725220 | 0.82 | RAB9A (0.69) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL476587 | 0.82 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL3776194 | 0.82 | HDAC6 (0.66) | HDAC6RAB9ASMN1; SMN2HTTKDM4E | |
| Ammonia Solution, Strong SCHEMBL28553547 | 0.82 | RAB9A (0.69) | HDAC6RAB9ASMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | PGLS, ABCG2, UGCG | HDAC6 359/4885RAB9A 1506/4885SMN1; SMN2 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.