⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930808 | 0.83 | — | — | |
| SCHEMBL11152868 | 0.82 | ALDH1A1 (0.60) | — | |
| SCHEMBL27893778 | 0.78 | — | — | |
| SCHEMBL26896 | 0.75 | ALDH1A1 (1.00) | — | |
| SCHEMBL5850539 | 0.73 | ALDH1A1 (0.63) | — | |
| Hydrochloric Acid SCHEMBL21956045 | 0.73 | ALDH1A1 (0.94) | — | |
| SCHEMBL8460588 | 0.73 | — | — | |
| SCHEMBL17333232 | 0.73 | ALDH1A1 (0.63) | — | |
| SCHEMBL499601 | 0.73 | ALDH1A1 (0.94) | — | |
| Hydrazine SCHEMBL28767472 | 0.72 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517002-A | Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | claimed |
| CN-112755193-A | Method of treating malignancies with anti-tyrosine kinase inhibitors using dianhydrogalactitol or a derivative thereof | 德玛医药 | 2021-05-07 | — | — | CN | disclosed |
| CN-101087800-B | Salts of isophosphoramide mustard and analogs thereof as antitumor agents | DEKK TEC INC | 2015-01-07 | — | — | CN | disclosed |
| US-8198247-B2 | Process for and intermediates in the preparation of canfosfamide and its salts | TELIK, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| CN-101087800-A | Salts of isophosphoramide mustard and analogs thereof as antitumor agents | DEKK TEC INC (US) | 2007-12-12 | — | — | CN | disclosed |
| US-20060135409-A1 | Process for and intermediates in the preparation of canfosfamide and its salts | TELIK, INC. | 2006-06-22 | — | — | US | disclosed |
| CN-1024544-C | Synergistic plant growth regulator compositions | UNION CARBIDE AGRICULT (US) | 1994-05-18 | — | — | CN | disclosed |
| WO-1989011278-A1 | CYCLOPHOSPHAMIDE ANALOGS USEFUL AS ANTI-TUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| US-4517002-A | Phosphorodiamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0119494-A1 | Urease inhibited urea based fertilizer compositions containing phosphorus compounds | ALLIED CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |