Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.64 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485043 | 0.83 | MEN1 (0.51) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL485045 | 0.83 | MEN1 (0.51) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL8516603 | 0.83 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL6361268 | 0.83 | ALDH1A1 (0.85) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL13131227 | 0.82 | MEN1 (0.49) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL484112 | 0.81 | PDE4A (0.52) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL484111 | 0.81 | PDE4A (0.52) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL3587605 | 0.81 | CNR1 (0.60) | TAS1R3TAS1R1TAS1R2ALDH1A1LMNA | |
| SCHEMBL6615213 | 0.81 | TAS1R3 (0.62) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL2077671 | 0.80 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738149-B1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 2006-11-29 | — | — | EP | disclosed |