Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CPA2 | P48052 | 1/20 | 0.42 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5971029 | 0.93 | SIRT5 (0.47) | CPA1CPA2CPA4SIRT5HDAC1 | |
| SCHEMBL5970299 | 0.88 | FNTA (0.46) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970238 | 0.87 | CPA1 (0.42) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970151 | 0.85 | CPA1 (0.46) | CPA1CPA2CPA4SIRT5PLG | |
| SCHEMBL5970128 | 0.84 | SIRT5 (0.44) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970243 | 0.83 | FNTA (0.45) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970177 | 0.83 | PLG (0.48) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970296 | 0.82 | CPA1 (0.43) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970389 | 0.82 | CPA1 (0.43) | CPA1CPA2CPA4SIRT5FNTA | |
| SCHEMBL5970592 | 0.82 | SIRT5 (0.54) | CPA1CPA2CPA4SIRT5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080070-B1 | ANTIANGIOGENIC DRUG TO TREAT CANCER, ARTHRITIS AND RETINOPATHY | ABBOTT LAB (US) | 2006-11-22 | — | — | EP | claimed |