Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.58 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.58 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.58 |
| ▸ | GAPDH | P04406 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | STAT6 | P42226 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597084 | 1.00 | LMNA (0.63) | LMNATP53NT5EHIF1AADORA2A | |
| SCHEMBL11811220 | 0.99 | LMNA (0.62) | LMNATP53NT5EHIF1AADORA2A | |
| SCHEMBL11805362 | 0.90 | LMNA (0.66) | LMNATP53NT5EHIF1AADORA2A | |
| Xanthosine SCHEMBL8665102 | 0.89 | LMNA (0.65) | LMNATP53NT5EHIF1AADORA2A | |
| Xanthosine SCHEMBL6676995 | 0.89 | LMNA (0.65) | LMNATP53NT5EHIF1AADORA2A | |
| Xanthosine SCHEMBL11523732 | 0.89 | LMNA (0.65) | LMNATP53NT5EHIF1AADORA2A | |
| Xanthosine SCHEMBL188120 | 0.89 | LMNA (0.65) | LMNATP53NT5EHIF1AADORA2A | |
| Xanthosine SCHEMBL5352244 | 0.88 | LMNA (0.63) | LMNATP53NT5EHIF1AADORA2A | |
| Guanosine SCHEMBL8661570 | 0.86 | CYP2C19 (0.73) | LMNANT5EHIF1AADORA2AADORA2B | |
| SCHEMBL6295569 | 0.86 | LMNA (0.77) | LMNATP53NT5EHIF1AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108392680-B | Plastic full-degradable hard tissue filling biological material | 珠海睿展生物材料有限公司 | 2020-12-18 | — | — | CN | claimed |
| CN-108392680-A | Biomaterial is filled by a kind of shaping degradable sclerous tissues | 苏州纳晶医药技术有限公司 | 2018-08-14 | — | — | CN | claimed |
| WO-2024073025-A1 | ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME | MARS, INCORPORATED (US) | 2024-04-04 | — | — | WO | disclosed |
| CN-108392680-B | Plastic full-degradable hard tissue filling biological material | 珠海睿展生物材料有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-108392680-A | Biomaterial is filled by a kind of shaping degradable sclerous tissues | 苏州纳晶医药技术有限公司 | 2018-08-14 | — | — | CN | disclosed |
| US-8440812-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2013-05-14 | — | — | US | disclosed |
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | GIULIANI INTERNATIONAL LIMITED | 2012-04-19 | — | — | US | disclosed |
| US-8114986-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-02-14 | — | — | US | disclosed |
| US-20100323980-A9 | Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2010-12-23 | — | — | US | disclosed |
| US-20090258837-A1 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-10-15 | — | — | US | disclosed |
| CN-101243102-A | Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | GIULIANI INT LTD (IE) | 2008-08-13 | — | — | CN | disclosed |
| EP-1907407-A1 | IMPROVEMENTS TO ANALOGOUS COMPOUNDS OF 6-THIOGUANOSINE TRIPHOSPHATE, THEIR USE IN MEDICAL FIELDS AND PROCESSES FOR THEIR PREPARATION | Giuliani International Limited (IE) | 2008-04-09 | — | — | EP | disclosed |
| CN-1300304-C | 5-amino-4-carbamyl imidazole nucleoside producing bacterium and preparation method thereof | GUANGDONG PROV MICROBE INST (CN) | 2007-02-14 | — | — | CN | disclosed |
| WO-2007010515-A1 | IMPROVEMENTS TO ANALOGOUS COMPOUNDS OF 6-THIOGUANOSINE TRIPHOSPHATE, THEIR USE IN MEDICAL FIELDS AND PROCESSES FOR THEIR PREPARATION | GIULIANI INTERNATIONAL LIMITED (IE) | 2007-01-25 | — | — | WO | disclosed |
| CN-1710065-A | 5-amino-4-carbamyl imidazole nucleoside producing bacterium and preparation method thereof | GUANGDONG PROV MICROBE INST (CN) | 2005-12-21 | — | — | CN | disclosed |
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0219838-A2 | Carbocyclic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258837-A1 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | TPMT, MTAP, G6PD | LMNA 4630/4885TP53 2809/4885NT5E 209/4885 |
| US-20120094948-A1 | Analogous Compounds of 6-Thioguanosine Triphosphate, their use in Medical Fields and Processes for their Preparation | TPMT, MTAP, G6PD | LMNA 4630/4885TP53 2809/4885NT5E 209/4885 |
| US-20100323980-A9 | Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | TPMT, G6PD, MTAP | LMNA 4616/4885TP53 3205/4885NT5E 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.