Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 16/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5970231 | 0.91 | ADORA2B (0.56) | ADORA2BXDH | |
| SCHEMBL5970374 | 0.85 | ADORA2B (0.48) | ADORA2BXDH | |
| SCHEMBL5970144 | 0.80 | ADORA2B (0.47) | ADORA2BXDH | |
| SCHEMBL5970362 | 0.79 | ADORA2B (0.52) | ADORA2BXDH | |
| SCHEMBL5970054 | 0.78 | ADORA2B (0.63) | ADORA2BXDH | |
| SCHEMBL5970239 | 0.77 | ADORA2B (0.51) | ADORA2BXDH | |
| SCHEMBL5970462 | 0.77 | ADORA2B (0.52) | ADORA2BXDH | |
| SCHEMBL1497200 | 0.76 | ADORA2B (0.59) | ADORA2B | |
| SCHEMBL5970527 | 0.75 | ADORA2B (0.57) | ADORA2BXDH | |
| SCHEMBL5970162 | 0.75 | ADORA2B (0.49) | ADORA2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658291-A2 | SUBSTITUTED 8-HETEROARYL XANTHINES | Adenosine Therapeutics, LLC (US) | 2006-05-24 | — | — | EP | claimed |
| WO-2005021548-A2 | SUBSTITUTED 8-HETEROARYL XANTHINES | ADENOSINE THERAPEUTICS, LLC (US) | 2005-03-10 | — | — | WO | claimed |