Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615136 | 0.93 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL14338942 | 0.82 | ALDH1A1 (0.50) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL5130515 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL14266750 | 0.81 | ALDH1A1 (0.55) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL14594524 | 0.81 | ALDH1A1 (0.38) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2769356 | 0.80 | AR (0.55) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL5972286 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL6358511 | 0.79 | MAPT (0.56) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL14003620 | 0.78 | ALDH1A1 (0.56) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28114517 | 0.78 | ALDH1A1 (0.62) | ALDH1A1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685090-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005042464-A1 | ANDROGEN RECEPTOR MODULATORS | KARO BIO AB (SE) | 2005-05-12 | — | — | WO | disclosed |