Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793965 | 0.80 | ADORA1 (1.00) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL5821367 | 0.75 | ADORA1 (0.86) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL5823674 | 0.75 | ADORA2A (1.00) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| Sch-58261 SCHEMBL537287 | 0.75 | ADORA2A (1.00) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL5823566 | 0.74 | ADORA3 (1.00) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL5821433 | 0.74 | ADORA1 (0.78) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL22358524 | 0.73 | ADORA1 (0.71) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL10329726 | 0.73 | ADORA2A (0.62) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL10330164 | 0.73 | ADORA2A (0.62) | ADORA1ADORA2ARAB9AADORA3NPC1 | |
| SCHEMBL29794067 | 0.73 | ADORA2A (0.62) | ADORA1ADORA2ARAB9AADORA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-A1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005039572-A1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-05-06 | — | — | WO | disclosed |