Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360577 | 0.71 | PDE5A (0.38) | PDE5ALMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL150334 | 0.61 | LMNA (0.77) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL18181415 | 0.61 | GAA (0.52) | LMNATSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31429963 | 0.60 | CA1 (0.77) | PDE5ALMNAALDH1A1HPGDKDM4E | |
| SCHEMBL5014792 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL545629 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20421629 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28935010 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1538013 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28934870 | 0.59 | LMNA (0.72) | LMNATSHRSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633818-A2 | ANTIMICROBIAL PIGMENTS | MERCK PATENT GmbH (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004092283-A2 | ANTIMICROBIAL PIGMENTS | MERCK PATENT GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |