⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009656 | 0.88 | HSD17B10 (0.31) | — | |
| SCHEMBL6035318 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL1224515 | 0.74 | CES2 (0.31) | — | |
| SCHEMBL18108040 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL8962666 | 0.72 | CES2 (0.39) | — | |
| SCHEMBL7022350 | 0.72 | — | — | |
| SCHEMBL7112938 | 0.71 | — | — | |
| SCHEMBL6824405 | 0.71 | TSHR (0.47) | — | |
| SCHEMBL8962458 | 0.71 | CES2 (0.38) | — | |
| SCHEMBL6034297 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208105-B1 | PROCESS FOR THE FORMATION OF POLYHEDRAL OLIGOMERIC SILSESQUIOXANES | HYBRID PLASTICS (US) | 2006-10-04 | — | — | EP | disclosed |
| US-6972312-B1 | Process for the formation of polyhedral oligomeric silsesquioxanes | HYBRID PLASTICS LLC (US) | 2005-12-06 | — | — | US | disclosed |
| US-20050239985-A1 | Process for the formation of polyhedral oligomeric silsesquioxanes | HYBRID PLASTICS LLC (US) | 2005-10-27 | — | — | US | disclosed |
| EP-1208105-A4 | PROCESS FOR THE FORMATION OF POLYHEDRAL OLIGOMERIC SILSESQUIOXANES | HYBRID PLASTICS (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-1208105-A1 | PROCESS FOR THE FORMATION OF POLYHEDRAL OLIGOMERIC SILSESQUIOXANES | Hybrid Plastics (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001010871-A1 | PROCESS FOR THE FORMATION OF POLYHEDRAL OLIGOMERIC SILSESQUIOXANES | HYBRID PLASTICS (US) | 2001-02-15 | — | — | WO | disclosed |
| EP-0080539-B1 | POLYMERS PRIMARILY FOR CONTACT LENSES, AND CONTACT LENSES MADE FROM THEM | Tsuetaki, George F. (US) | 1986-05-07 | — | — | EP | disclosed |
| EP-0080539-A1 | Polymers primarily for contact lenses, and contact lenses made from them | Tsuetaki, George F. (US) | 1983-06-08 | — | — | EP | disclosed |
| WO-1983001777-A1 | IMPROVED OXYGEN PERMEABLE HARD AND SEMI-HARD CONTACT LENS COMPOSITIONS, METHODS AND ARTICLES OF MANUFACTURE | TSUETAKI GEORGE F (US) | 1983-05-26 | — | — | WO | disclosed |
| US-4303772-A | COPOLYMER OF POLYSILOXANYL ALKYL ACRYLATES OR METHACRYLATES, FREE RADICAL CATALYST | Tsuetaki, George F. (US) | 1981-12-01 | — | — | US | disclosed |