SCHEMBL6824405

SCHEMBL6824405

C=C(C)C(=O)O[Si](Cl)(Cl)CCCC

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 4/20 0.37
THRB P10828 2/20 0.36
TP53 P04637 1/20 0.31
CES1 P23141 1/20 0.30
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009658 0.88 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL1525545 0.80 TSHR (0.50) TSHRALDH1A1THRBCES1THRA
SCHEMBL7191288 0.78 TSHR (0.48) TSHRALDH1A1THRBTP53CES1
SCHEMBL5838985 0.78 TSHR (0.48) TSHRALDH1A1THRBCES1THRA
SCHEMBL7186339 0.77 TSHR (0.47) TSHRALDH1A1THRBCES1THRA
SCHEMBL5838917 0.76 TSHR (0.55) TSHRALDH1A1THRBCES1THRA
SCHEMBL3111019 0.76 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL8962671 0.75 TSHR (0.64) TSHRALDH1A1THRBTP53
SCHEMBL27812601 0.75 TSHR (0.64) TSHRALDH1A1THRB
SCHEMBL5838837 0.74 TSHR (0.53) TSHRALDH1A1THRBCES1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202535-B2 Method for treating subterranean formations LAMBERTI SPA (IT) 2019-02-12 US disclosed
US-20170247597-A1 METHOD FOR TREATING SUBTERRANEAN FORMATIONS LAMBERTI SPA (IT) 2017-08-31 US disclosed
WO-2016030165-A1 METHOD FOR TREATING SUBTERRANEAN FORMATIONS LAMBERTI SPA (IT) 2016-03-03 WO disclosed
EP-1381331-A2 COLORED PRINTING INK FOR CONTACT LENSES Novartis AG (CH) 2004-01-21 EP disclosed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO disclosed