Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL3911029 | 1.00 | — | — | |
| Propene SCHEMBL27869633 | 1.00 | TSHR (0.55) | — | |
| Propene SCHEMBL28752304 | 0.96 | — | — | |
| Propene SCHEMBL11800016 | 0.96 | TSHR (0.50) | — | |
| Propene SCHEMBL28214323 | 0.96 | — | — | |
| Propene SCHEMBL19874990 | 0.96 | — | — | |
| Ethylene Glycol SCHEMBL332774 | 0.92 | TSHR (0.46) | — | |
| Ethylene Glycol SCHEMBL8333223 | 0.92 | TSHR (0.46) | — | |
| Ethylene Glycol SCHEMBL1879522 | 0.92 | TSHR (0.46) | — | |
| Ethylene Glycol SCHEMBL1115046 | 0.89 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109679034-A | A kind of high-adaptability ester group modified polycarboxylic acid water-reducing agent and its preparation and application | 上海东大化学有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109642206-A | Anti-infective fatty acid esters in fermentation | 普拉克生化公司 | 2019-04-16 | — | — | CN | claimed |
| US-8933112-B2 | Topical liquid to ameliorate pain and promote healing of burn-injured skin | Memphaceuticals, LLC (US) | 2015-01-13 | — | — | US | claimed |
| CN-102875309-B | Method for preparing propylene from ethanol | CHINA PETROLEUM & CHEMICAL | 2014-09-10 | — | — | CN | claimed |
| US-20130338206-A1 | TOPICAL LIQUID TO AMELIORATE PAIN AND PROMOTE HEALING OF BURN-INJURED SKIN | ROBERTS, LEE K. | 2013-12-19 | — | — | US | claimed |
| CN-102875309-A | Method for preparing propylene from ethanol | CHINA PETROLEUM & CHEMICAL | 2013-01-16 | — | — | CN | claimed |
| US-20100216751-A1 | Liquid Bevirimat Dosage Forms for Oral Administration | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | claimed |
| US-20100163021-A1 | SYSTEM FOR DELIVERING NEBULIZED CYCLOSPORINE AND METHODS OF TREATMENT | NOVARTIS PHARMA AG (CH) | 2010-07-01 | — | — | US | claimed |
| CN-101389370-A | System for delivering nebulized cyclosporine and methods of treatment | NOVARTIS PHARMA AG (CH) | 2009-03-18 | — | — | CN | claimed |
| EP-1988956-A2 | SYSTEM FOR DELIVERING NEBULIZED CYCLOSPORINE AND METHODS OF TREATMENT | Novartis Pharma AG (CH) | 2008-11-12 | — | — | EP | claimed |
| WO-2007100741-A2 | SYSTEM FOR DELIVERING NEBULIZED CYCLOSPORINE AND METHODS OF TREATMENT | NOVARTIS PHARMA AG (CH) | 2007-09-07 | — | — | WO | claimed |
| CN-1053439-C | Synthesis of flame-retardant monomer containing carbon-carbon unsaturated bond s-triazine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2000-06-14 | — | — | CN | claimed |
| EP-0868170-A1 | COMPOSITION BASE FOR TOPICAL THERAPEUTIC AND COSMETIC PREPARATIONS | JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. (US) | 1998-10-07 | — | — | EP | claimed |
| WO-1998010742-A1 | COMPOSITION BASE FOR TOPICAL THERAPEUTIC AND COSMETIC PREPARATIONS | JOHNSON & JOHNSON CONSUMER PRODUCTS (US) | 1998-03-19 | — | — | WO | claimed |
| CN-1114313-A | Synthesis of flame-retardant monomer containing carbon-carbon unsaturated link sym-triazinyl | CHANGCHUN APPLIED CHEMISTRY (CN) | 1996-01-03 | — | — | CN | claimed |
| CN-2158518-Y | Combined structure of ice product raw material rapid heating barrel and cooling barrel | LI MINGTANG (CN) | 1994-03-09 | — | — | CN | claimed |
| CN-117916233-A | Amorphous, crystalline, pharmaceutical compositions, methods of preparation and uses of thiohydantoin compounds or pharmaceutically acceptable salts thereof | 苏州开拓药业股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117045598-A | Preparation method of digoxin injection with stable quality | 上海旭东海普药业有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-1993012789-A1 | USE OF SPIPERONE OR SPIPERONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS | BETH ISRAEL HOSPITAL (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0181184-A2 | Drug dispenser | Medipen Limited (GB) | 1986-05-14 | — | — | EP | disclosed |