Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1879522 | 0.96 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL332774 | 0.96 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL8333223 | 0.96 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL206376 | 0.93 | — | — | |
| Propene SCHEMBL19874990 | 0.93 | — | — | |
| Ethylene Glycol SCHEMBL4769225 | 0.89 | TSHR (0.46) | TSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL3200076 | 0.89 | TSHR (0.46) | TSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL3171689 | 0.89 | TSHR (0.46) | TSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL9756248 | 0.89 | TSHR (0.46) | TSHRALDH1A1 | |
| Ethylene Glycol SCHEMBL622577 | 0.89 | TSHR (0.46) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648696-B2 | containing alcohol, water and a glycol; rapid drug delivery; bioavailability | UNIMED PHARMACEUTICALS, LLC (US) | 2010-01-19 | — | — | US | claimed |
| US-20040162336-A1 | Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent | ALKEM LABORATORIES LIMITED (IN) | 2004-08-19 | — | — | US | claimed |
| US-6747058-B1 | FAST-ACTING DELIVERY SYSTEM FOR DELTA-9-TETRAHYDROCANNABINOL TO IMPROVE BIOAVAILABILITY | UNIMED PHARMACEUTICALS, INC. | 2004-06-08 | — | — | US | claimed |
| US-11813237-B2 | Creatine, its derivatives, compositions and methods of use thereof | YU RUEY J (US) | 2023-11-14 | — | — | US | disclosed |
| US-11642328-B2 | Creatine, its derivatives, compositions and methods of use thereof | YU RUEY J (US) | 2023-05-09 | — | — | US | disclosed |
| US-20220401398-A1 | CREATINE, ITS DERIVATIVES, COMPOSITIONS AND METHODS OF USE THEREOF | YU RUEY J (US) | 2022-12-22 | — | — | US | disclosed |
| US-10660872-B2 | Methods for treatment of cognitive decline | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-05-26 | — | — | US | disclosed |
| US-10617612-B2 | Composition comprising decanal or as active ingredients for preventing hair loss or stimulating hair growth | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2020-04-14 | — | — | US | disclosed |
| US-20190151256-A1 | Composition Including Nonanal As Active Ingredient For Preventing Hair Loss Or Stimulating Hair Development | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2019-05-23 | — | — | US | disclosed |
| US-20180104162-A1 | COMPOSITION COMPRISING DECANAL OR AS ACTIVE INGREDIENTS FOR PREVENTING HAIR LOSS OR STIMULATING HAIR GROWTH | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI U NIVERSITY (KR) | 2018-04-19 | — | — | US | disclosed |
| US-20170333387-A1 | METHODS FOR TREATMENT OF COGNITIVE DECLINE | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2017-11-23 | — | — | US | disclosed |
| US-20070072939-A1 | Cannabinoid active pharmaceutical ingredient for improved dosage forms | EURO-CELTIQUE, S.A. | 2007-03-29 | — | — | US | disclosed |
| WO-2006133941-A2 | CANNABINOID ACTIVE PHARMACEUTICAL INGREDIENT FOR IMPROVED DOSAGE FORMS | EURO-CELTIQUE S.A. (LU) | 2006-12-21 | — | — | WO | disclosed |
| EP-1212039-B1 | COMPOSITION FOR INHALATION COMPRISING DELTA-9-TETRAHYDROCANNABINOL IN A SEMIAQUEOUS SOLVENT | UNIMED PHARMACEUTICALS INC (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20040162336-A1 | Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent | ALKEM LABORATORIES LIMITED (IN) | 2004-08-19 | — | — | US | disclosed |
| US-20040162336-A1 | Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent | ALKEM LABORATORIES LIMITED (IN) | 2004-08-19 | — | — | US | disclosed |
| US-6747058-B1 | FAST-ACTING DELIVERY SYSTEM FOR DELTA-9-TETRAHYDROCANNABINOL TO IMPROVE BIOAVAILABILITY | UNIMED PHARMACEUTICALS, INC. | 2004-06-08 | — | — | US | disclosed |
| US-5578377-A | ANTIREFLECTIVE FILM | ASAHI GLASS COMPANY LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| WO-1994020066-A1 | SUNSCREEN COMPOSITION | UNILEVER PLC (GB) | 1994-09-15 | — | — | WO | disclosed |
| US-5306486-A | Residue-free | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1994-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151256-A1 | Composition Including Nonanal As Active Ingredient For Preventing Hair Loss Or Stimulating Hair Development | FGF1, TYR, PTPN6 | TSHR 1632/4885ALDH1A1 1815/4885SMN1; SMN2 4070/4885 |
| US-20070072939-A1 | Cannabinoid active pharmaceutical ingredient for improved dosage forms | CNR2, CNR1, OPRD1 | TSHR 3100/4885ALDH1A1 4272/4885SMN1; SMN2 2325/4885 |
| US-10617612-B2 | Composition comprising decanal or as active ingredients for preventing hair loss or stimulating hair growth | TYR, CUTA, FGF1 | TSHR 1524/4885ALDH1A1 882/4885SMN1; SMN2 3100/4885 |
| US-20180104162-A1 | COMPOSITION COMPRISING DECANAL OR AS ACTIVE INGREDIENTS FOR PREVENTING HAIR LOSS OR STIMULATING HAIR GROWTH | TYR, CUTA, FGF1 | TSHR 1524/4885ALDH1A1 882/4885SMN1; SMN2 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.