⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21901723 | 0.79 | — | — | |
| SCHEMBL2682415 | 0.78 | GAA (0.60) | — | |
| SCHEMBL4677300 | 0.77 | GAA (0.52) | — | |
| Formaldehyde SCHEMBL9514376 | 0.77 | GAA (0.52) | — | |
| SCHEMBL77241 | 0.76 | — | — | |
| SCHEMBL123093 | 0.76 | — | — | |
| SCHEMBL27411503 | 0.76 | ALDH1A1 (0.63) | — | |
| SCHEMBL9995139 | 0.76 | — | — | |
| SCHEMBL9838596 | 0.75 | ALDH1A1 (0.81) | — | |
| SCHEMBL5364605 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149439-A1 | PYRIDYLMETHYSULFONE DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-06-11 | — | — | US | claimed |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | claimed |
| EP-1867636-A1 | PYRIDYLMETHYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2007-12-19 | — | — | EP | claimed |
| US-20070281959-A1 | Glucocorticoid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-12-06 | — | — | US | claimed |
| EP-1718653-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | Ligand Pharmaceuticals Inc. (US) | 2006-11-08 | — | — | EP | claimed |
| WO-2005082909-A1 | GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2005-09-09 | — | — | WO | claimed |
| EP-0832082-B1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-11-21 | — | — | EP | claimed |
| EP-0832082-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040681-A1 | N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1996-12-19 | — | — | WO | claimed |
| US-4144240-A | USED FOR MODIFYING CEPHALOSPORINS | PFIZER INC. (US) | 1979-03-13 | — | — | US | claimed |
| US-8114886-B2 | Pyridylmethylsulfone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-14 | — | — | US | disclosed |
| US-7556911-B2 | Titanocene based compound, photosensitive composition, photosensitive transfer sheet and pattern forming method | FUJIFILM CORPORATION (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20090149439-A1 | PYRIDYLMETHYSULFONE DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090105292-A9 | Glucocorticoid Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| EP-1867636-A1 | PYRIDYLMETHYLSULFONE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-0156771-A2 | Cephalosporins | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1985-10-02 | — | — | EP | disclosed |
| US-4477448-A | CONTAIN PYRAZOLE SUBSTITUENTS | SANDOZ LTD. (CH) | 1984-10-16 | — | — | US | disclosed |
| EP-0037380-B1 | NEW PROCESS FOR THE PRODUCTION OF CEPHALOSPORIN ANTIBIOTICS, AND NOVEL INTERMEDIATES USED IN SUCH PROCESS AND THEIR PRODUCTION | BIOCHEMIE Gesellschaft m.b.H. (AT) | 1984-09-12 | — | — | EP | disclosed |
| WO-1984000547-A1 | FLUORALKYLATEDCARBAPENEM DERIVATIVES | SANDOZ AG (AT) | 1984-02-16 | — | — | WO | disclosed |
| EP-0037380-A2 | New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production | BIOCHEMIE Gesellschaft m.b.H. (AT) | 1981-10-07 | — | — | EP | disclosed |