Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 7/20 | 0.51 |
| ▸ | FEN1 | P39748 | 7/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266327 | 0.87 | PKM (0.60) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL5268313 | 0.83 | PKM (0.56) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL4780674 | 0.82 | PKM (0.70) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL1516211 | 0.81 | PKM (0.64) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL18250062 | 0.79 | PKM (0.61) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL1366438 | 0.77 | PKM (1.00) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL12282858 | 0.75 | PKM (0.52) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL9590857 | 0.75 | PKM (0.68) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL5899359 | 0.74 | PKM (0.62) | PKMHDAC6TUBB4ATUBBTUBA3C | |
| SCHEMBL5899360 | 0.74 | PKM (0.62) | PKMHDAC6TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |