Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573030 | 0.91 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5573795 | 0.82 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5982035 | 0.78 | TUBB4A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5572465 | 0.75 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL26494977 | 0.74 | MAPT (0.62) | CNR2KDRMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL30373905 | 0.74 | MAPT (0.62) | CNR2KDRMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL6195457 | 0.73 | TUBB4A (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29409455 | 0.73 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5346065 | 0.73 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4019994 | 0.72 | PDE4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641777-A1 | INDOLE DERIVATIVES WITH APOPTOSIS-INDUCING EFFECT | Zentaris GmbH (DE) | 2006-04-05 | — | — | EP | claimed |
| EP-1595878-A1 | INDOLE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY | Zentaris GmbH (DE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004108702-A1 | INDOLE DERIVATIVES WITH APOPTOSIS-INDUCING EFFECT | ZENTARIS GMBH (DE) | 2004-12-16 | — | — | WO | claimed |
| EP-1484329-A1 | Indole derivatives with apoptosis inducing activity | Zentaris GmbH (DE) | 2004-12-08 | — | — | EP | claimed |
| EP-1641777-A1 | INDOLE DERIVATIVES WITH APOPTOSIS-INDUCING EFFECT | Zentaris GmbH (DE) | 2006-04-05 | — | — | EP | disclosed |
| EP-1595878-A1 | INDOLE DERIVATIVES WITH APOPTOSIS INDUCING ACTIVITY | Zentaris GmbH (DE) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004108702-A1 | INDOLE DERIVATIVES WITH APOPTOSIS-INDUCING EFFECT | ZENTARIS GMBH (DE) | 2004-12-16 | — | — | WO | disclosed |
| EP-1484329-A1 | Indole derivatives with apoptosis inducing activity | Zentaris GmbH (DE) | 2004-12-08 | — | — | EP | disclosed |