Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981957 | 1.00 | MAPK1 (0.61) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL55926 | 0.87 | SLC2A1 (0.75) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL11327801 | 0.85 | ALDH1A1 (0.63) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL2872287 | 0.84 | SLC2A1 (0.72) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL3217829 | 0.84 | ALDH1A1 (0.81) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL3217840 | 0.84 | ALDH1A1 (0.81) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL1405467 | 0.84 | ALDH1A1 (0.81) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL3217836 | 0.84 | ALDH1A1 (0.81) | MAPK1ALDH1A1TDP1HSD17B10TSHR | |
| SCHEMBL1405603 | 0.84 | CA1 (0.65) | MAPK1TDP1TSHRGSK3BNPC1 | |
| SCHEMBL1405466 | 0.84 | ALDH1A1 (0.81) | MAPK1ALDH1A1TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | claimed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | claimed |
| EP-2931714-B1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| WO-2014090364-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2014-06-19 | — | — | WO | disclosed |
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | disclosed |
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0446731-B1 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203067-A1 | Pesticidal compositions and methods | ACHE, DDT, PTMS | MAPK1 4785/4885ALDH1A1 3205/4885TDP1 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.