Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982965 | 0.87 | CYP3A4 (0.48) | USP2CYP3A4KCNH2NR1I2ADRB1 | |
| SCHEMBL4937196 | 0.78 | PTGER4 (0.54) | USP2CYP3A4KCNH2NR1I2ADRB1 | |
| SCHEMBL20897899 | 0.74 | KDM4E (0.66) | USP2CYP3A4KCNH2NR1I2ADRB1 | |
| SCHEMBL4946083 | 0.74 | HDAC1 (0.39) | USP2CYP3A4KCNH2NR1I2ADRB1 | |
| SCHEMBL2128961 | 0.71 | MAOB (0.52) | USP2CYP3A4KCNH2NR1I2ADRB1 | |
| SCHEMBL4087358 | 0.71 | PTGER4 (0.55) | KDM4EMEN1KMT2A | |
| SCHEMBL11039373 | 0.69 | ADRB1 (0.55) | ADRB1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL4709035 | 0.69 | MAOB (0.77) | FFAR4FFAR1MRGPRX4MAOBNR4A2 | |
| SCHEMBL5295666 | 0.69 | MEN1 (0.49) | KDM4ETDP1MEN1KMT2AHDAC1 | |
| SCHEMBL22442339 | 0.67 | MGLL (0.53) | USP2CYP3A4KCNH2NR1I2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |