Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943525 | 0.92 | PTGER4 (0.51) | PTGER4PTGER2MTOR | |
| SCHEMBL5982548 | 0.89 | PTGER4 (0.45) | PTGER4PTGER2ADRB1ADRB3 | |
| SCHEMBL5983282 | 0.88 | BCL2 (0.43) | PTGER4PTGER2ADRB1ADRB3 | |
| SCHEMBL5992349 | 0.88 | PTGER4 (0.51) | PTGER4PTGER2 | |
| SCHEMBL5983008 | 0.88 | PTGER4 (0.51) | PTGER4PTGER2 | |
| SCHEMBL5990886 | 0.86 | PTGER4 (0.53) | PTGER4PTGER2ADRB1 | |
| SCHEMBL5982209 | 0.86 | ACACB (0.39) | PTGER4PTGER2 | |
| SCHEMBL5983187 | 0.86 | PTGER4 (0.37) | PTGER4PTGER2ADRB1ADRB3 | |
| SCHEMBL5988841 | 0.83 | ALDH1A1 (0.41) | PTGER4PTGER2ADRB1ADRB3 | |
| SCHEMBL5983445 | 0.83 | PTGER4 (0.40) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | claimed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | claimed |
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |