Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943283 | 0.91 | PTGER4 (0.40) | PTGER4PTGER2TBXA2RPTGER3OPRM1 | |
| SCHEMBL5982548 | 0.91 | PTGER4 (0.45) | PTGER4PTGER2OPRM1OPRD1OPRK1 | |
| SCHEMBL5988841 | 0.89 | ALDH1A1 (0.41) | PTGER4PTGER2NPC1RAB9AALDH1A1 | |
| SCHEMBL5983008 | 0.89 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RPTGER3OPRM1 | |
| SCHEMBL5981555 | 0.85 | ACACB (0.47) | PTGER4PTGER2 | |
| SCHEMBL5982999 | 0.83 | KMT2A (0.39) | PTGER4PTGER2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5983075 | 0.83 | PTGER4 (0.51) | PTGER4PTGER2 | |
| SCHEMBL5992349 | 0.83 | PTGER4 (0.51) | PTGER4PTGER2TBXA2RPTGER3NPC1 | |
| SCHEMBL5983282 | 0.83 | BCL2 (0.43) | PTGER4PTGER2 | |
| SCHEMBL5990886 | 0.82 | PTGER4 (0.53) | PTGER4PTGER2TBXA2ROPRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |