Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5982835 | 0.86 | MEN1 (0.53) | KCNK3MEN1KMT2AKCNK9HTT | |
| Hydrochloric Acid SCHEMBL5983863 | 0.80 | RAB9A (0.47) | LMNASMN1; SMN2HTTMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5983348 | 0.79 | SMN1; SMN2 (0.53) | KCNK3SMN1; SMN2MEN1KMT2AKCNK9 | |
| Hydrochloric Acid SCHEMBL5983919 | 0.78 | F2R (0.52) | LMNAMEN1KMT2ARXFP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5983763 | 0.78 | KCNK3 (0.49) | KCNK3MEN1KMT2AKCNK9RXFP1 | |
| Hydrochloric Acid SCHEMBL5983539 | 0.77 | PTGS1 (0.56) | KCNK3MEN1KMT2AKCNK9RXFP1 | |
| Hydrochloric Acid SCHEMBL5983492 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL2550898 | 0.76 | DDB1 (0.36) | — | |
| SCHEMBL5983644 | 0.76 | RXFP1 (0.43) | RXFP1 | |
| Hydrochloric Acid SCHEMBL5983356 | 0.76 | TLR7 (0.48) | SMN1; SMN2GAAL3MBTL1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663971-A1 | SUBSTITUTED 2-CARBONYLAMINO-6-PIPERIDINAMINOPYRIDINES AND SUBSTITUTED 1-CARBONYLAMINO-3-PIPERIDINAMINOBENZENES AS 5-HT1F AGONISTS | Eli Lilly and Company (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005035499-A1 | SUBSTITUTED 2-CARBONYLAMINO-6-PIPERIDINAMINOPYRIDINES AND SUBSTITUTED 1-CARBONYLAMINO-3-PIPERIDINAMINOBENZENES AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |