Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983472 | 0.90 | MEN1 (0.43) | FLT3MEN1KMT2ASORT1CDK2 | |
| SCHEMBL5983275 | 0.90 | MEN1 (0.54) | FLT3MEN1KMT2ACDK2CCNA2 | |
| SCHEMBL5984129 | 0.88 | CDK2 (0.45) | FLT3CDK2CCNA2MAPK7CCNA1 | |
| SCHEMBL5983641 | 0.87 | FLT3 (0.45) | FLT3SORT1CDK2CCNA2CHRM1 | |
| Hydrochloric Acid SCHEMBL5984136 | 0.84 | HTR1F (0.51) | FLT3MEN1KMT2ACDK2CCNA2 | |
| SCHEMBL12020910 | 0.82 | SLC6A2 (0.44) | FLT3MEN1KMT2ASORT1HTR1F | |
| Hydrochloric Acid SCHEMBL5983739 | 0.81 | CCNA2 (0.45) | FLT3KMT2ACDK2CCNA2CHRM1 | |
| SCHEMBL12021012 | 0.81 | HTR1F (0.50) | FLT3MEN1KMT2ACDK2CCNA2 | |
| Hydrochloric Acid SCHEMBL5983376 | 0.80 | HTR1F (0.49) | FLT3MEN1KMT2ACDK2CCNA2 | |
| SCHEMBL5983475 | 0.79 | HTR1F (0.48) | FLT3MEN1KMT2AHTR1FL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663971-A1 | SUBSTITUTED 2-CARBONYLAMINO-6-PIPERIDINAMINOPYRIDINES AND SUBSTITUTED 1-CARBONYLAMINO-3-PIPERIDINAMINOBENZENES AS 5-HT1F AGONISTS | Eli Lilly and Company (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005035499-A1 | SUBSTITUTED 2-CARBONYLAMINO-6-PIPERIDINAMINOPYRIDINES AND SUBSTITUTED 1-CARBONYLAMINO-3-PIPERIDINAMINOBENZENES AS 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |