Glycerin

Glycerin

SCHEMBL5983875

O=C(O)Oc1ccc([N+](=O)[O-])cc1.OCC(O)CO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ BCL9 O00512 1/20 0.51
▸ CTNNB1 P35222 1/20 0.51
▸ GAA P10253 2/20 0.50
▸ SRD5A2 P31213 2/20 0.48
▸ ALDH1A1 P00352 3/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ PKM P14618 2/20 0.47
▸ MGLL Q99685 2/20 0.46
▸ MEN1 O00255 2/20 0.45
▸ HTR2A P28223 1/20 0.45
▸ MAPK1 P28482 1/20 0.44
▸ ALOX5 P09917 1/20 0.44
▸ PTPN7 P35236 1/20 0.44
▸ PTPN12 Q05209 1/20 0.44
▸ PTPN22 Q9Y2R2 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL5476136 0.87 BCL9 (0.57) BCL9CTNNB1GAASRD5A2ALDH1A1
SCHEMBL26375 0.87 GAA (0.62) BCL9CTNNB1GAASRD5A2ALDH1A1
Alcohol SCHEMBL23927970 0.85 BCL9 (0.64) BCL9CTNNB1GAASRD5A2ALDH1A1
Bicarbonate SCHEMBL7985678 0.85 GAA (0.61) BCL9CTNNB1GAASRD5A2ALDH1A1
Hydrochloric Acid SCHEMBL7895039 0.85 GAA (0.61) BCL9CTNNB1GAASRD5A2ALDH1A1
Bromide SCHEMBL30468845 0.85 GAA (0.61) BCL9CTNNB1GAASRD5A2ALDH1A1
Bicarbonate SCHEMBL9330234 0.82 GAA (0.57) BCL9CTNNB1GAASRD5A2ALDH1A1
SCHEMBL26654348 0.82 GAA (0.57) BCL9CTNNB1GAASRD5A2ALDH1A1
Acetic Acid SCHEMBL28965273 0.82 GAA (0.62) BCL9CTNNB1GAASRD5A2ALDH1A1
Cyclohexane SCHEMBL30739999 0.82 GAA (0.57) BCL9CTNNB1GAASRD5A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1691780-A2 GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION ALZA CORPORATION (US) 2006-08-23 — — EP disclosed
WO-2005051351-A2 GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION ALZA CORPORATION (US) 2005-06-09 — — WO disclosed
EP-1465599-A1 LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID ALZA Corporation (US) 2004-10-13 — — EP disclosed
WO-2003053409-A1 LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID ALZA CORPORATION (US) 2003-07-03 — — WO disclosed
EP-1223916-A2 NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY ALZA Corporation (US) 2002-07-24 — — EP disclosed
WO-2001026629-A2 NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY ALZA CORPORATION (US) 2001-04-19 — — WO disclosed
WO-2001026625-A2 NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY ALZA CORP (US) 2001-04-19 — — WO disclosed
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