Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985547 | 0.87 | HTR2A (0.56) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| SCHEMBL13369008 | 0.84 | HTR2A (0.53) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| SCHEMBL29870688 | 0.82 | HTR2A (0.56) | HTR2AKMT2ABCL9CTNNB1GAA | |
| SCHEMBL2597348 | 0.82 | HTR2A (0.64) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| SCHEMBL763026 | 0.82 | HTR2A (0.64) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| SCHEMBL5526504 | 0.82 | HTR2A (0.58) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| Glycerin SCHEMBL5983875 | 0.81 | BCL9 (0.51) | HTR2AKMT2AMEN1BCL9CTNNB1 | |
| SCHEMBL1496537 | 0.80 | GAA (0.68) | KMT2AMEN1GAAALDH1A1PKM | |
| SCHEMBL31639396 | 0.80 | HTR2A (0.57) | HTR2AKMT2ABCL9CTNNB1GAA | |
| SCHEMBL21097206 | 0.80 | HTR2A (0.61) | HTR2AKMT2ABCL9CTNNB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013002969-A1 | ACID-LABILE LIPOPHILIC PRODRUGS OF CANCER CHEMOTHERAPEUTIC AGENTS | Arbor Therapeutics, LLC (US) | 2013-01-03 | — | — | WO | disclosed |
| EP-1691780-A2 | GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION | ALZA CORPORATION (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005051351-A2 | GENE DELIVERY MEDIATED BY LIPOSOME-DNA COMPLEX WITH CLEAVABLE PEG SURFACE MODIFICATION | ALZA CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| EP-1465599-A1 | LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID | ALZA Corporation (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003053409-A1 | LIPOSOME COMPOSITION FOR DELIVERY OF NUCLEIC ACID | ALZA CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |
| EP-1223916-A2 | NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY | ALZA Corporation (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001026629-A2 | NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY | ALZA CORPORATION (US) | 2001-04-19 | — | — | WO | disclosed |
| WO-2001026625-A2 | NEUTRAL-CATIONIC LIPID FOR NUCLEIC ACID AND DRUG DELIVERY | ALZA CORP (US) | 2001-04-19 | — | — | WO | disclosed |