⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221838 | 0.84 | — | — | |
| SCHEMBL1483796 | 0.83 | LMNA (0.38) | — | |
| SCHEMBL29676 | 0.81 | — | — | |
| SCHEMBL11238093 | 0.79 | LMNA (0.30) | — | |
| SCHEMBL603698 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL103113 | 0.79 | LMNA (0.43) | — | |
| SCHEMBL5661656 | 0.79 | — | — | |
| SCHEMBL83492 | 0.77 | — | — | |
| SCHEMBL17607771 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL93158 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018993-B2 | Antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20030158164-A1 | Novel antiandrogenic agent | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1304334-A1 | NOVEL ANTIANDROGENIC AGENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6410523-B1 | BONE DEFECTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-06-25 | — | — | US | disclosed |
| US-20020045772-A1 | Vitamin D derivative having substituent at 2beta-position | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1070704-A1 | VITAMIN D DERIVATIVES SUBSTITUTED AT THE 2$g(b)-POSITION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0207889-B1 | PROCESS FOR THE PREPARATION OF METALLOCENE COMPLEXES | CIBA-GEIGY AG (CH) | 1988-07-20 | — | — | EP | disclosed |