Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601852 | 0.72 | — | — | |
| SCHEMBL3970277 | 0.68 | NOS1 (0.32) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL28324669 | 0.67 | ALOX15 (0.33) | CA1CA2CA4 | |
| SCHEMBL27720943 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL28305967 | 0.67 | ALOX15 (0.33) | CA1CA2CA4 | |
| SCHEMBL8062277 | 0.65 | — | — | |
| SCHEMBL14734513 | 0.64 | CHRM2 (0.37) | CA1CA2CA4 | |
| SCHEMBL22096194 | 0.64 | NOS1 (0.32) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL16411466 | 0.64 | — | — | |
| SCHEMBL14616020 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447264-A1 | N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |