Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17407541 | 0.79 | TSHR (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31090051 | 0.72 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL18896033 | 0.70 | TSHR (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL26075366 | 0.67 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10359572 | 0.64 | CA1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL15989333 | 0.64 | TSHR (0.38) | CA1CA2ALDH1A1HDAC6SIGMAR1 | |
| SCHEMBL26075163 | 0.63 | CA1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22909156 | 0.63 | CA1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL17296510 | 0.63 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2347469 | 0.62 | CA1 (0.71) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114280-B2 | Separation matrix and method of purification | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2012-02-14 | — | — | US | disclosed |
| US-20070196858-A1 | Separation Matrix And Method Of Purification | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2007-08-23 | — | — | US | disclosed |