SCHEMBL17407541

SCHEMBL17407541

CN(C)CCNS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ALDH1A1 P00352 3/20 0.48
CA2 P00918 6/20 0.44
CA1 P00915 5/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
GAA P10253 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ALOX15 P16050 1/20 0.39
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18896033 0.90 TSHR (0.44) TSHRNPSR1ALDH1A1CA2CA1
SCHEMBL15989333 0.82 TSHR (0.38) TSHRNPSR1ALDH1A1CA2CA1
SCHEMBL598733 0.79 CA1 (0.43) ALDH1A1CA2CA1MMP1MMP2
SCHEMBL31090051 0.74 CA1 (0.52) ALDH1A1CA2CA1CYP2C19MMP1
SCHEMBL19563408 0.73 SIGMAR1 (0.71) TSHRNPSR1ALDH1A1CA2CA1
SCHEMBL26075366 0.73 CA1 (0.50) ALDH1A1CA2CA1CYP2C9MMP1
SCHEMBL10359572 0.69 CA1 (0.46) CA2CA1MMP1MMP2MMP9
SCHEMBL1348432 0.68 CYP2C9 (0.50) TSHRNPSR1ALDH1A1CA2CYP2C9
SCHEMBL26075163 0.68 CA1 (0.45) TSHRALDH1A1CA2CA1MMP1
SCHEMBL22909156 0.68 CA1 (0.45) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3548462-B1 ENERGY PROVIDING DEVICES AND APPLICATION THEREOF UNIV CALIFORNIA (US) 2025-03-19 EP disclosed
US-11258134-B2 Energy providing devices and applications thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-22 US disclosed
US-11258134-B2 Energy providing devices and applications thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-22 US disclosed
US-11084002-B2 Universal scalable and cost-effective surface modifications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-08-10 US disclosed
US-20200203692-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-06-25 US disclosed
US-20200203692-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-06-25 US disclosed
US-10629880-B2 Energy providing devices and applications thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-21 US disclosed
US-10629880-B2 Energy providing devices and applications thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-21 US disclosed
US-20190351375-A1 UNIVERSAL SCALABLE AND COST-EFFECTIVE SURFACE MODIFICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-11-21 US disclosed
EP-3548462-A1 ENERGY PROVIDING DEVICES AND APPLICATION THEREOF The Regents of The University of California (US) 2019-10-09 EP disclosed
US-10315169-B2 Universal scalable and cost-effective surface modifications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-06-11 US disclosed
US-20180159106-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF NATIONAL SCIENCE FOUNDATION 2018-06-07 US disclosed
US-20180159106-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF NATIONAL SCIENCE FOUNDATION 2018-06-07 US disclosed
WO-2018102517-A1 ENERGY PROVIDING DEVICES AND APPLICATION THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-07 WO disclosed
US-20170296986-A1 UNIVERSAL SCALABLE AND COST-EFFECTIVE SURFACE MODIFICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-10-19 US disclosed
US-20170296986-A1 UNIVERSAL SCALABLE AND COST-EFFECTIVE SURFACE MODIFICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-10-19 US disclosed
US-9662617-B2 Universal scalable and cost-effective surface modifications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-30 US disclosed
US-9662617-B2 Universal scalable and cost-effective surface modifications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-30 US disclosed
US-20160001236-A1 Universal Scalable and Cost-Effective Surface Modifications NATIONAL SCIENCE FOUNDATION 2016-01-07 US disclosed
US-20160001236-A1 Universal Scalable and Cost-Effective Surface Modifications NATIONAL SCIENCE FOUNDATION 2016-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160001236-A1 Universal Scalable and Cost-Effective Surface Modifications EPCAM, CD59, SIGLEC9 TSHR 2555/4885NPSR1 3462/4885ALDH1A1 2394/4885
US-20190351375-A1 UNIVERSAL SCALABLE AND COST-EFFECTIVE SURFACE MODIFICATIONS EPCAM, CD59, SIGLEC9 TSHR 2555/4885NPSR1 3462/4885ALDH1A1 2394/4885
US-20200203692-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF PC, IDH2, MCU TSHR 4492/4885NPSR1 3361/4885ALDH1A1 1627/4885
US-11258134-B2 Energy providing devices and applications thereof PC, IDH2, MCU TSHR 4492/4885NPSR1 3361/4885ALDH1A1 1627/4885
US-20180159106-A1 ENERGY PROVIDING DEVICES AND APPLICATIONS THEREOF PC, IDH2, MCU TSHR 4492/4885NPSR1 3361/4885ALDH1A1 1627/4885
US-20170296986-A1 UNIVERSAL SCALABLE AND COST-EFFECTIVE SURFACE MODIFICATIONS EPCAM, CD59, SIGLEC9 TSHR 2555/4885NPSR1 3462/4885ALDH1A1 2394/4885
US-10315169-B2 Universal scalable and cost-effective surface modifications EPCAM, CD59, SIGLEC9 TSHR 2555/4885NPSR1 3462/4885ALDH1A1 2394/4885
US-11084002-B2 Universal scalable and cost-effective surface modifications EPCAM, CD59, SIGLEC9 TSHR 2555/4885NPSR1 3462/4885ALDH1A1 2394/4885
US-10629880-B2 Energy providing devices and applications thereof PC, IDH2, MCU TSHR 4492/4885NPSR1 3361/4885ALDH1A1 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.