Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.45 |
| ▸ | CA2 | P00918 | 15/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359572 | 0.81 | CA1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL26075366 | 0.76 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL26075163 | 0.71 | CA1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31066637 | 0.71 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4817325 | 0.71 | ALDH1A1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL12580638 | 0.71 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4818467 | 0.68 | GBA1 (0.51) | CA12CA9 | |
| SCHEMBL31090051 | 0.68 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28574756 | 0.68 | PGR (0.31) | — | |
| SCHEMBL17407541 | 0.68 | TSHR (0.49) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |