Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586992 | 1.00 | SIGMAR1 (0.47) | SIGMAR1TMEM97 | |
| SCHEMBL582233 | 0.85 | SIGMAR1 (0.47) | SIGMAR1TMEM97 | |
| SCHEMBL586828 | 0.84 | PLG (0.47) | — | |
| SCHEMBL586903 | 0.80 | SMN1; SMN2 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL2991986 | 0.77 | TMEM97 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL2991989 | 0.77 | TMEM97 (0.51) | SIGMAR1TMEM97 | |
| SCHEMBL586922 | 0.77 | ALDH1A1 (0.49) | SIGMAR1TMEM97 | |
| SCHEMBL587119 | 0.74 | SIGMAR1 (0.45) | SIGMAR1TMEM97 | |
| SCHEMBL15017310 | 0.73 | SMN1; SMN2 (0.57) | — | |
| SCHEMBL581230 | 0.73 | PLG (0.46) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417131-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |