Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599132 | 0.93 | KMT2A (0.47) | KMT2AMEN1NPSR1P2RY12ACKR3 | |
| Hydrochloric Acid SCHEMBL3001555 | 0.88 | ALDH1A1 (0.39) | NPSR1ALDH1A1KDM4ECD274GAA | |
| SCHEMBL598877 | 0.82 | GAA (0.45) | KMT2AMEN1NPSR1ALDH1A1KDM4E | |
| SCHEMBL598054 | 0.82 | PKM (0.43) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL599362 | 0.82 | ALDH1A1 (0.45) | KMT2AMEN1NPSR1ALDH1A1KDM4E | |
| SCHEMBL599631 | 0.81 | KDM4E (0.48) | KMT2AMEN1NPSR1ALDH1A1KDM4E | |
| SCHEMBL598268 | 0.80 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL599366 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL599063 | 0.79 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL3008541 | 0.79 | GAA (0.47) | ALDH1A1KDM4EHSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114894-B2 | Bicyclic compounds and methods of making and using same | NANOTHERAPEUTICS, INC. (US) | 2012-02-14 | — | — | US | disclosed |