Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648685 | 0.84 | TDP1 (0.59) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL4648692 | 0.84 | TDP1 (0.59) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL14487931 | 0.84 | TDP1 (0.59) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL8750848 | 0.81 | MAPT (0.53) | LMNATDP1GSK3BF3MEN1 | |
| SCHEMBL4212357 | 0.81 | TDP1 (0.61) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL5513071 | 0.81 | TDP1 (0.61) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL1514193 | 0.79 | GSK3B (0.65) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL29170010 | 0.79 | GSK3B (0.65) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL14487924 | 0.78 | TDP1 (0.59) | LMNATDP1GSK3BF3THRB | |
| SCHEMBL18338902 | 0.77 | F3 (0.66) | LMNATDP1GSK3BF3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1700593-A1 | Water-in-Oil dispersion comprising dextran fatty acid ester | Shiseido Company, Limited (JP) | 2006-09-13 | — | — | EP | disclosed |
| EP-1468663-A2 | Oil-water mixed composition | SHISEIDO COMPANY LIMITED (JP) | 2004-10-20 | — | — | EP | disclosed |
| EP-1354580-A1 | AGENTS FOR INHIBITING OR RESTORING SKIN DAMAGE CAUSED BY DRYING AND METHOD OF EVALUATING THE SAME | SHISEIDO COMPANY LIMITED (JP) | 2003-10-22 | — | — | EP | disclosed |