Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14487931 | 1.00 | TDP1 (0.59) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL4648685 | 1.00 | TDP1 (0.59) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL5987989 | 0.84 | LMNA (0.58) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL2135879 | 0.82 | KMT2A (0.66) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL2135887 | 0.82 | KMT2A (0.66) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL14487924 | 0.82 | TDP1 (0.59) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL5513071 | 0.81 | TDP1 (0.61) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL4212357 | 0.81 | TDP1 (0.61) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL2139845 | 0.81 | KMT2A (0.61) | TDP1LMNAKMT2AMEN1CASP3 | |
| SCHEMBL2139839 | 0.81 | KMT2A (0.61) | TDP1LMNAKMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960342-A1 | ERYTHRULOSE ESTERS AS UV FILTERS | Merck Patent GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007065524-A1 | ERYTHRULOSE ESTERS AS UV FILTERS | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |