Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.41 |
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987163 | 0.90 | CTSS (0.38) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5986840 | 0.86 | CTSS (0.41) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5987022 | 0.86 | CTSS (0.41) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5987765 | 0.86 | CTSS (0.41) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5987068 | 0.85 | CTSS (0.39) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5987193 | 0.84 | CTSS (0.39) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5987708 | 0.84 | CTSK (0.39) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5985409 | 0.84 | KDM4E (0.39) | CTSSCTSKACECTSBPTPN1 | |
| SCHEMBL5986225 | 0.83 | NPC1 (0.39) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL5986230 | 0.83 | NPC1 (0.39) | CTSSCTSKACECTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045545-B1 | Aminoalkylbenzofurans as serotonin (5-HT(2c)) agonists | ELI LILLY AND COMPANY (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |