Glycoursodeoxycholic Acid

Glycoursodeoxycholic Acid

SCHEMBL59881

C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 11/20 1.00
NR1H4 Q96RI1 6/20 1.00
ABCB11 O95342 5/20 1.00
ENPP2 Q13822 3/20 1.00
SLC10A2 Q12908 4/20 0.80
KMT2A Q03164 3/20 0.80
MEN1 O00255 2/20 0.80
LMNA P02545 1/20 0.80
CYP2C19 P33261 1/20 0.80
CHRM2 P08172 1/20 0.80
ADRA2A P08913 1/20 0.80
ADRA1A P35348 1/20 0.80
TDP1 Q9NUW8 1/20 0.80
SLC10A1 Q14973 1/20 0.80
CISD1 Q9NZ45 1/20 0.80
CYP3A4 P08684 1/20 0.80
VDR P11473 1/20 0.78
EPHA2 P29317 1/20 0.78
NR3C1 P04150 1/20 0.76
ABCC4 O15439 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycoursodeoxycholic Acid SCHEMBL20204267 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL13851608 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL11962429 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL28793575 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL9151495 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL12917601 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycochenodeoxycholate SCHEMBL236354 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL935341 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL10694925 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL1219678 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3943 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122075506-A Soluble powder and application thereof in treating avian coccidiosis 2026-05-26 CN claimed
CN-122056828-A Industrial preparation method of vitamin K1 micelle injection preparation 浙江创新生物有限公司 2026-05-19 CN claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
CN-122017068-A Bile acid high-flux detection method based on ultra-high performance liquid chromatography tandem mass spectrometry and application thereof 青岛百谱生物科技有限公司 2026-05-12 CN claimed
EP-4705289-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2026-03-11 EP claimed
US-12569502-B2 Use of bile acids and derivatives thereof in preparation of GPR39 agonist PEKING UNIVERSITY (CN) 2026-03-10 US claimed
CN-121577901-A Urine metabolism marker combination for distinguishing benign kidney diseases from kidney cancers and application thereof 哈尔滨脉图精准技术有限公司 2026-02-27 CN claimed
EP-4262876-B1 COVALENTLY MODIFIED ANTIGENS FOR IMPROVED IMMUNE RESPONSE AND/OR STABILITY DEFENCE THERAPEUTICS INC (CA) 2026-02-25 EP claimed
EP-0813421-A1 LIQUID FORMULATIONS FOR PROTEINIC PHARMACEUTICALS COMPRISING AT LEAST 2 ABSORPTION ENHANCERS MODI, Pankaj (CA) 1997-12-29 EP claimed
EP-0799030-A1 POWDER FORMULATIONS CONTAINING MELEZITOSE AS A DILUENT Astra Aktiebolag (SE) 1997-10-08 EP claimed
US-5653987-A FOR ORAL DELIVERY OF INSULIN MODI PANKAJ (CA) 1997-08-05 US claimed
WO-1996036352-A1 LIQUID FORMULATIONS FOR PROTEINIC PHARMACEUTICALS COMPRISING AT LEAST 2 ABSORPTION ENHANCERS MODI PANKAJ (CA) 1996-11-21 WO claimed
WO-1996019207-A1 POWDER FORMULATIONS CONTAINING MELEZITOSE AS A DILUENT ASTRA AKTIEBOLAG (SE) 1996-06-27 WO claimed
US-5010056-A Growth disorders PIERREL SPA (IT) 1991-04-23 US claimed
EP-0301392-A1 Pharmaceutical composition for intranasal administration comprising GH - Releasing hormone, a cholinergic agonist and in case a bile salt Pierrel S.p.A. (IT) 1989-02-01 EP claimed
EP-0273469-A1 Oral pharmaceutical compositions with sustained release Gipharmex S.p.A. (IT) 1988-07-06 EP claimed
US-4164573-A INSULIN GALINSKY ALVIN M 1979-08-14 US claimed
US-4158707-A Parenteral preparations HOFFMANN-LA ROCHE INC. (US) 1979-06-19 US claimed