Glycochenodeoxycholate

Glycochenodeoxycholate

SCHEMBL236354

C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 11/20 1.00
NR1H4 Q96RI1 6/20 1.00
ABCB11 O95342 5/20 1.00
ENPP2 Q13822 3/20 1.00
SLC10A2 Q12908 4/20 0.80
KMT2A Q03164 3/20 0.80
MEN1 O00255 2/20 0.80
LMNA P02545 1/20 0.80
CYP2C19 P33261 1/20 0.80
CHRM2 P08172 1/20 0.80
ADRA2A P08913 1/20 0.80
ADRA1A P35348 1/20 0.80
TDP1 Q9NUW8 1/20 0.80
SLC10A1 Q14973 1/20 0.80
CISD1 Q9NZ45 1/20 0.80
CYP3A4 P08684 1/20 0.80
VDR P11473 1/20 0.78
EPHA2 P29317 1/20 0.78
NR3C1 P04150 1/20 0.76
ABCC4 O15439 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycoursodeoxycholic Acid SCHEMBL20204267 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL13851608 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL11962429 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL28793575 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL9151495 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL12917601 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL59881 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL935341 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL10694925 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2
Glycoursodeoxycholic Acid SCHEMBL1219678 1.00 GPBAR1 (1.00) GPBAR1NR1H4ABCB11ENPP2SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
US-20260139227-A1 ADIPOSE-DERIVED REGENERATIVE CELL PREPARATIONS BLUE CELL THERAPEUTICS APS (DK) 2026-05-21 US claimed
US-12569502-B2 Use of bile acids and derivatives thereof in preparation of GPR39 agonist PEKING UNIVERSITY (CN) 2026-03-10 US claimed
EP-4701625-A2 FORMULATION OF THERAPEUTIC AGENTS FOR IMPROVED PERMEATION Vivtex Corporation (US) 2026-03-04 EP claimed
EP-4262876-B1 COVALENTLY MODIFIED ANTIGENS FOR IMPROVED IMMUNE RESPONSE AND/OR STABILITY DEFENCE THERAPEUTICS INC (CA) 2026-02-25 EP claimed
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
EP-4638478-A1 COVALENTLY-MODIFIED STEROID ACID-PEPTIDES HAVING ENHANCED STABILITY AND/OR BIOLOGICAL ACTIVITY Defence Therapeutics Inc. (CA) 2025-10-29 EP claimed
US-20250273338-A1 BIOMARKERS FOR DETECTING COLORECTAL CANCER OR COLORECTAL ADENOMA AND METHODS THEREOF Precogify Pharmaceutical China Co., Ltd. (CN) 2025-08-28 US claimed
US-20250251371-A1 Method for Identifying Calculus Bovis and Substitute Thereof, and Use Thereof ANHUI UNIVERSITY OF CHINESE MEDICINE (CN) 2025-08-07 US claimed
US-12350346-B2 Conjugates enhancing total cellular accumulation DEFENCE THERAPEUTICS INC. (CA) 2025-07-08 US claimed
WO-2001012155-A1 COMPOSITIONS AND METHODS FOR ENHANCED ABSORPTION OF HYDROPHILIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2001-02-22 WO claimed
WO-2001009163-A2 IMPROVEMENT OF PEPTIDE TRANSPORT BY CONJUGATION WITH BILE ACIDS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2001-02-08 WO claimed
WO-2001001960-A1 CLEAR OIL-CONTAINING PHARMACEUTICAL COMPOSITIONS LIPOCINE, INC. (US) 2001-01-11 WO claimed
WO-2000050007-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF HYDROPHOBIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2000-08-31 WO claimed
US-6040188-A MEASURING HYDROCARBON CONTAMINANTS IN SOIL BY MIXING SAMPLE WITH MIXTURE OF LIPIDS AND BILE SALTS, FORMING MICELLES; ALLOW SAMPLE-LIPID-BILE SALT MIXTURE COMPOSITION TO SEPARATE INTO LIQUID PHASE AND SOLID PHASE; MEASURE CONTAMINANTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-03-21 US claimed
EP-0910411-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES Cortecs (UK) Limited (GB) 1999-04-28 EP claimed
WO-1998000169-A1 HYDROPHOBIC PREPARATIONS CONTAINING MEDIUM CHAIN MONOGLYCERIDES CORTECS (UK) LIMITED) (GB) 1998-01-08 WO claimed
EP-0813421-A1 LIQUID FORMULATIONS FOR PROTEINIC PHARMACEUTICALS COMPRISING AT LEAST 2 ABSORPTION ENHANCERS MODI, Pankaj (CA) 1997-12-29 EP claimed
US-5653987-A FOR ORAL DELIVERY OF INSULIN MODI PANKAJ (CA) 1997-08-05 US claimed
WO-1996036352-A1 LIQUID FORMULATIONS FOR PROTEINIC PHARMACEUTICALS COMPRISING AT LEAST 2 ABSORPTION ENHANCERS MODI PANKAJ (CA) 1996-11-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139227-A1 ADIPOSE-DERIVED REGENERATIVE CELL PREPARATIONS CXCL12, FGF2, FABP4 GPBAR1 3626/4885NR1H4 3664/4885ABCB11 2764/4885
US-12569502-B2 Use of bile acids and derivatives thereof in preparation of GPR39 agonist GPR39, GPBAR1, GPR119 GPBAR1 2/4885NR1H4 8/4885ABCB11 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.