Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 1.00 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 5/20 | 1.00 |
| ▸ | ENPP2 | Q13822 | 3/20 | 1.00 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.80 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | VDR | P11473 | 1/20 | 0.78 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.76 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycoursodeoxycholic Acid SCHEMBL20204267 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL13851608 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL11962429 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL28793575 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL9151495 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL12917601 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycochenodeoxycholate SCHEMBL236354 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL59881 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL935341 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 | |
| Glycoursodeoxycholic Acid SCHEMBL1219678 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11ENPP2SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273469-A1 | Oral pharmaceutical compositions with sustained release | Gipharmex S.p.A. (IT) | 1988-07-06 | — | — | EP | claimed |
| US-10166246-B2 | TGR5 agonist complexes for treating diabetes and cancer | CITY OF HOPE (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170196890-A1 | TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER | CITY OF HOPE | 2017-07-13 | — | — | US | disclosed |
| WO-2015183794-A1 | TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER | CITY OF HOPE (US) | 2015-12-03 | — | — | WO | disclosed |
| EP-0273469-A1 | Oral pharmaceutical compositions with sustained release | Gipharmex S.p.A. (IT) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10166246-B2 | TGR5 agonist complexes for treating diabetes and cancer | GLP1R, GCGR, GPR119 | GPBAR1 6/4885NR1H4 95/4885ABCB11 2077/4885 |
| US-20170196890-A1 | TGR5 AGONIST COMPLEXES FOR TREATING DIABETES AND CANCER | GLP1R, GCGR, GPR119 | GPBAR1 6/4885NR1H4 95/4885ABCB11 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.