Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399258 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399397 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399233 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399426 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399377 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399458 | 0.76 | GFER (0.52) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399287 | 0.76 | HPGD (0.48) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399417 | 0.75 | MAPT (0.47) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399418 | 0.74 | BRPF1 (0.48) | ALDH1A1MEN1MAPTKMT2AHPGD | |
| SCHEMBL1399354 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-A1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | H.Lundbeck A/S (DK) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061455-A1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | H. LUNDBECK A/S (DK) | 2005-07-07 | — | — | WO | disclosed |