Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522006 | 0.81 | PPARD (0.65) | PPARDPPARGL3MBTL1FFAR4FFAR1 | |
| SCHEMBL5989333 | 0.79 | PPARD (0.50) | PPARDPPARGL3MBTL1HTTPPARA | |
| SCHEMBL5992347 | 0.79 | PPARD (0.50) | PPARDPPARGL3MBTL1HTTPPARA | |
| SCHEMBL5990106 | 0.79 | PPARG (0.73) | PPARDPPARGFFAR4FFAR1PPARA | |
| SCHEMBL5990103 | 0.79 | PPARG (0.73) | PPARDPPARGFFAR4FFAR1PPARA | |
| SCHEMBL5989516 | 0.76 | PPARG (0.65) | PPARDPPARGL3MBTL1FFAR4FFAR1 | |
| SCHEMBL5989519 | 0.76 | PPARG (0.65) | PPARDPPARGL3MBTL1FFAR4FFAR1 | |
| Metaxon SCHEMBL28111499 | 0.75 | PPARD (0.67) | PPARDPPARGL3MBTL1HTTTP53 | |
| Metaxon SCHEMBL117877 | 0.75 | TDP1 (0.70) | PPARDPPARGHTTMAPTPTGDR2 | |
| SCHEMBL5988869 | 0.75 | PPARD (0.58) | PPARDPPARGL3MBTL1PPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |