Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990326 | 0.84 | SCN8A (0.49) | ARSCN8ASCN10AHTTSLC6A2 | |
| SCHEMBL12180463 | 0.81 | GPR3 (0.44) | GRIN2BCA12CA1CA2CA7 | |
| SCHEMBL12422184 | 0.81 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13680420 | 0.79 | SLC6A4 (0.58) | ARSCN8ASCN10ABCAT1BCAT2 | |
| SCHEMBL8302095 | 0.77 | GPR3 (0.44) | ALPLCA12CA1CA2CA7 | |
| SCHEMBL8014909 | 0.75 | CA1 (0.62) | ARALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL5990449 | 0.74 | AR (0.50) | ARHTTCA12CA1CA2 | |
| SCHEMBL23957964 | 0.73 | AR (0.56) | ARBCAT1BCAT2ALDH1A1MAPK1 | |
| SCHEMBL20650170 | 0.73 | GPR3 (0.46) | MAPK1GRIN2BSLC6A2SLC6A3 | |
| SCHEMBL3033181 | 0.73 | RUNX1 (0.42) | ALDH1A1GRIN2BALPLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |