Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690257 | 0.84 | ALDH1A1 (0.59) | SLC6A4ARSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL3748487 | 0.81 | AR (0.54) | SLC6A4ARSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL5990326 | 0.80 | SCN8A (0.49) | SLC6A4SLC6A3SLC6A2ARSMN1; SMN2 | |
| SCHEMBL3755350 | 0.80 | ALDH1A1 (0.53) | SLC6A4SLC6A3SLC6A2ARSMN1; SMN2 | |
| SCHEMBL257293 | 0.80 | HSD11B1 (0.44) | SLC6A4SLC6A3SLC6A2ARSMN1; SMN2 | |
| SCHEMBL5990167 | 0.79 | AR (0.49) | SLC6A4SLC6A3SLC6A2ARALDH1A1 | |
| SCHEMBL22199038 | 0.79 | GPR3 (0.47) | SLC6A4SLC6A3SLC6A2ARSCN8A | |
| SCHEMBL12301144 | 0.78 | RXRA (0.54) | SLC6A4SLC6A3SLC6A2SMN1; SMN2NPC1 | |
| SCHEMBL172615 | 0.78 | HTR2A (0.55) | SLC6A4ARSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL28816731 | 0.78 | LTA4H (0.55) | SLC6A4SLC6A2ARSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582664-B2 | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-01 | — | — | US | disclosed |