Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.70 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.68 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427709 | 1.00 | ACAT1 (0.70) | ACAT1SOAT1GPR132 | |
| SCHEMBL8329032 | 0.96 | ACAT1 (0.64) | ACAT1SOAT1GPR132 | |
| SCHEMBL7642220 | 0.95 | ACAT1 (0.71) | ACAT1SOAT1GPR132 | |
| SCHEMBL8327420 | 0.94 | ACAT1 (0.68) | ACAT1SOAT1GPR132 | |
| SCHEMBL8327532 | 0.94 | ACAT1 (0.73) | ACAT1SOAT1 | |
| SCHEMBL8327121 | 0.94 | ACAT1 (0.61) | ACAT1SOAT1GPR132 | |
| SCHEMBL8327777 | 0.94 | ACAT1 (0.61) | ACAT1SOAT1GPR132 | |
| SCHEMBL8324735 | 0.94 | ACAT1 (0.72) | ACAT1SOAT1 | |
| SCHEMBL7608958 | 0.93 | ACAT1 (0.67) | ACAT1SOAT1 | |
| SCHEMBL8327724 | 0.93 | ACAT1 (0.63) | ACAT1SOAT1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006063066-A | MEDICINAL COMPOSITION HAVING ANTI-ARTERIOSCLEROTIC ACTION | SANKYO CO LTD | 2006-03-09 | — | — | JP | disclosed |
| EP-0842933-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0842933-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-05-20 | — | — | EP | disclosed |