Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.72 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.71 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636784 | 0.95 | ACAT1 (0.72) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6635287 | 0.94 | ACAT1 (0.72) | ACAT1SOAT1PDE4AKCNH2MAPT | |
| SCHEMBL29427709 | 0.94 | ACAT1 (0.70) | ACAT1SOAT1 | |
| SCHEMBL5990213 | 0.94 | ACAT1 (0.70) | ACAT1SOAT1 | |
| SCHEMBL8330841 | 0.93 | ACAT1 (0.69) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8330165 | 0.92 | ACAT1 (0.68) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327196 | 0.92 | ACAT1 (0.68) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327488 | 0.92 | ACAT1 (0.68) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL6637175 | 0.92 | ACAT1 (0.72) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327206 | 0.91 | ACAT1 (0.81) | ACAT1SOAT1PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0901489-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044339-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-11-27 | — | — | WO | disclosed |