⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167804 | 0.81 | — | — | |
| SCHEMBL13066227 | 0.81 | — | — | |
| SCHEMBL28391810 | 0.81 | — | — | |
| SCHEMBL1696874 | 0.79 | — | — | |
| SCHEMBL515343 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL29074311 | 0.79 | TXN (0.44) | — | |
| SCHEMBL9459934 | 0.79 | — | — | |
| SCHEMBL9460139 | 0.79 | — | — | |
| SCHEMBL10556487 | 0.79 | — | — | |
| SCHEMBL10696546 | 0.79 | FPR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015315-B1 | Gapped oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2006-03-21 | — | — | US | disclosed |
| US-5955589-A | WITH ONE SEGMENT HAVING TWO CONSECUTIVE NUCLEOTIDES WITH 2' FLUORINE, SECOND SEGMENT WITH FIVE CONSECUTIVE NUCLEOTIDES WITH 2' HYDROGEN; HYBRIDIZES WITH HIGHER BINDING AFFINITY; FOR DIAGNOSIS, ANTISENSE THERAPY | ISIS PHARMACEUTICALS INC. (US) | 1999-09-21 | — | — | US | disclosed |