Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025938 | 0.87 | MRGPRX4 (0.69) | MRGPRX4NR4A2MAOBPPARGPPARA | |
| SCHEMBL6231474 | 0.82 | MRGPRX4 (0.63) | MRGPRX4NR4A2MAOB | |
| SCHEMBL10536447 | 0.81 | MRGPRX4 (0.52) | MRGPRX4NR4A2PPARGPPARAKDM4E | |
| SCHEMBL5669711 | 0.81 | MAOB (0.74) | MRGPRX4NR4A2MAOBL3MBTL1IDO1 | |
| SCHEMBL30810364 | 0.80 | IDO1 (0.66) | NR4A2MAOBIDO1KMT2AFFAR1 | |
| SCHEMBL3158759 | 0.80 | TSHR (0.64) | NR4A2MAOBL3MBTL1IDO1LMNA | |
| SCHEMBL12072717 | 0.80 | L3MBTL1 (0.60) | MRGPRX4MAOBPPARGPPARAKDM4E | |
| SCHEMBL11019942 | 0.78 | DRD2 (0.55) | NR4A2MAOBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10335673 | 0.78 | MAOB (0.65) | MRGPRX4NR4A2MAOBLMNAPKM | |
| SCHEMBL16024758 | 0.77 | L3MBTL1 (0.50) | MRGPRX4MAOBKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |