Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567835 | 0.83 | CTSK (0.53) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL14820895 | 0.82 | CTSK (0.57) | CTSKCTSSPPARAPPARGCTSL | |
| SCHEMBL148099 | 0.80 | CA1 (0.52) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL148100 | 0.80 | CA1 (0.52) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL17957327 | 0.80 | CA1 (0.52) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL256594 | 0.80 | CA1 (0.52) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL29480433 | 0.80 | CTSK (0.50) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL29480432 | 0.80 | CTSK (0.50) | CTSKCTSSCTSLCTSBMAPT | |
| Benzaldehyde SCHEMBL11503729 | 0.79 | PPARA (0.46) | CTSKCTSSPPARAPPARGCTSL | |
| Hydrochloric Acid SCHEMBL30428440 | 0.78 | CA1 (0.50) | CTSKCTSSCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087729-B1 | Peptide conjugates for the stabilization of membrane proteins and interactions with biological membranes | UNIVERSITY HEALTH NETWORK (CA) | 2006-08-08 | — | — | US | disclosed |
| EP-1196434-A2 | PEPTIDE CONJUGATES FOR THE STABILIZATION OF MEMBRANE PROTEINS AND INTERACTIONS WITH BIOLOGICAL MEMBRANES | University Health Network (CA) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002425-A2 | PEPTIDE CONJUGATES FOR THE STABILIZATION OF MEMBRANE PROTEINS AND INTERACTIONS WITH BIOLOGICAL MEMBRANES | UNIVERSITY HEALTH NETWORK (CA) | 2001-01-11 | — | — | WO | disclosed |