Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TLR3 | O15455 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889411 | 1.00 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL2889409 | 1.00 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL13199557 | 0.90 | GRIN2B (0.47) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| Fumaric Acid SCHEMBL5868233 | 0.84 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2889324 | 0.81 | KCNE1 (0.38) | ALDH1A1MAPK1LMNAKCNA5 | |
| SCHEMBL2889326 | 0.81 | KCNE1 (0.38) | ALDH1A1MAPK1LMNAKCNA5 | |
| SCHEMBL2900873 | 0.81 | KCNE1 (0.38) | ALDH1A1MAPK1LMNAKCNA5 | |
| Hydrochloric Acid SCHEMBL2900903 | 0.80 | KCNE1 (0.37) | ALDH1A1MAPK1LMNAKCNA5 | |
| Hydrochloric Acid SCHEMBL2887368 | 0.80 | KCNE1 (0.37) | ALDH1A1MAPK1LMNAKCNA5 | |
| Hydrochloric Acid SCHEMBL2887370 | 0.80 | KCNE1 (0.37) | ALDH1A1MAPK1LMNAKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-1718629-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR THE TREATMENT OF ARRHYTMIA | Nissan Chemical Industries, Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080368-A2 | BENZOPYRAN COMPOUND USEFUL FOR THE TREATMENT OF ARRHYTMIA | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | WO | disclosed |