Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27672981 | 0.87 | FABP4 (0.53) | KMT2AKDM4ETHRBALDH1A1HDAC3 | |
| SCHEMBL27652940 | 0.85 | FABP4 (0.51) | KMT2AKDM4EPOLBTHRBALDH1A1 | |
| SCHEMBL28326333 | 0.84 | THRB (0.48) | KMT2AKDM4ETHRBHTTMEN1 | |
| SCHEMBL4864708 | 0.82 | THRB (0.47) | KMT2APOLBTHRBHTTMEN1 | |
| SCHEMBL3199664 | 0.82 | MAPT (0.67) | KMT2APOLBALDH1A1HSD17B10HTT | |
| SCHEMBL3214608 | 0.80 | POLB (0.64) | KMT2AKDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL13603822 | 0.79 | KDM4E (0.45) | KMT2AKDM4ETHRBALDH1A1HTT | |
| SCHEMBL4865806 | 0.78 | TOP2A (0.48) | KMT2AKDM4EPOLBTHRBALDH1A1 | |
| SCHEMBL4740356 | 0.78 | THRB (0.64) | POLBTHRBALDH1A1HTTMAPT | |
| SCHEMBL4962925 | 0.77 | THRB (0.46) | KMT2APOLBTHRBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38970-E1 | Indolyl or indolinyl derivatives and medicinal use thereof as ACAT or lipid peroxidation inhibitors | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2006-02-07 | — | — | US | disclosed |
| EP-0866059-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND MEDICINAL USE THEREOF | KYOTO PHARMA IND (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-6200988-B1 | TETRAHYDROQUINOLINE DERIVATES; INHIBITORS OF ACYL COA:CHOLESTEROL ACYLTRANSFERASE AND LIPOPEROXIDATION; ARTERIOSCLEROSIS: CARDIOVASCULAR AND BRAIN DISORDERS | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| US-6063806-A | CARBOXY ACID OR ESTER DERIVATIVES OF INDOLINE OR INDOLE | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0866059-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1998-09-23 | — | — | EP | disclosed |