Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 1.00 |
| ▸ | NOS2 | P35228 | 4/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432593 | 1.00 | NOS3 (1.00) | NOS3NOS2DYRK1ANOS1KDM4E | |
| Bromide SCHEMBL5756062 | 0.98 | NOS3 (0.96) | NOS3NOS2DYRK1ANOS1KDM4E | |
| Hydrochloric Acid SCHEMBL31372470 | 0.98 | NOS3 (0.96) | NOS3NOS2DYRK1ANOS1KDM4E | |
| SCHEMBL9629714 | 0.83 | NOS3 (0.69) | NOS3NOS2DYRK1AKDM4EBACE1 | |
| SCHEMBL16637988 | 0.83 | NOS3 (0.70) | NOS3NOS2DYRK1ANOS1KDM4E | |
| SCHEMBL16671291 | 0.83 | NOS3 (0.70) | NOS3NOS2DYRK1ANOS1KDM4E | |
| SCHEMBL14637261 | 0.83 | NOS3 (0.70) | NOS3NOS2DYRK1ANOS1KDM4E | |
| SCHEMBL2640650 | 0.79 | NOS3 (0.63) | NOS3NOS2KDM4EMAPT | |
| SCHEMBL22670291 | 0.78 | NOS3 (0.63) | NOS3NOS2DYRK1ANOS1KDM4E | |
| SCHEMBL29433371 | 0.78 | NOS3 (0.63) | NOS3NOS2DYRK1ANOS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119432148-A | Perovskite ink, perovskite film and battery device | 云南大学 | 2025-02-14 | — | — | CN | claimed |
| CN-114790168-B | Preparation method of 2-amino-4-trifluoromethyl pyridine and 2-amino-4-trifluoromethyl pyridine | 上海素馨化工科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117165078-A | Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2023-12-05 | — | — | CN | claimed |
| US-20230014057-A1 | TREATMENT OF SKIN DISORDERS | TORQUR AG (CH) | 2023-01-19 | — | — | US | claimed |
| CN-115385852-A | Efficient synthesis method of 2-amino-4-trifluoromethylpyridine | 湖南阿斯迪康药业有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-114790168-A | Preparation method of 2-amino-4-trifluoromethylpyridine and 2-amino-4-trifluoromethylpyridine | 上海素馨化工科技有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-113150229-B | High-carbon-residue fluorine-containing pyridine type benzoxazine resin and preparation method thereof | 中北大学 | 2022-07-05 | — | — | CN | claimed |
| CN-113150229-A | High-carbon-residue fluorine-containing pyridine type benzoxazine resin and preparation method thereof | 中北大学 | 2021-07-23 | — | — | CN | claimed |
| CN-112480018-A | TRPV3 small-molecule allosteric inhibitor and preparation method thereof | 中国药科大学 | 2021-03-12 | — | — | CN | claimed |
| EP-3383391-A1 | TREATMENT OF CANCER WITH A PI3K INHIBITOR IN A PATIENT PRESELECTED FOR HAVING A PIK3CA MUTATION IN THE CTDNA | Novartis AG (CH) | 2018-10-10 | — | — | EP | claimed |
| US-20080146547-A1 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-06-19 | — | — | US | claimed |
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | claimed |
| WO-2008061108-A2 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | claimed |
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-14 | — | — | US | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | claimed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | claimed |
| EP-0228846-B1 | AMINO-TRIFLUOROMETHYLPYRIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-22 | — | — | EP | claimed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | claimed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039464-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | NOS3 2847/4885NOS2 2686/4885DYRK1A 2790/4885 |
| US-20080146547-A1 | PHTHALAZINE DERIVATIVES | CDK5, HIPK2, PACSIN2 | NOS3 3442/4885NOS2 3357/4885DYRK1A 2135/4885 |
| US-20230014057-A1 | TREATMENT OF SKIN DISORDERS | RXFP3, CCR3, CBR3 | NOS3 340/4885NOS2 1357/4885DYRK1A 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.