Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.63 |
| ▸ | NOS2 | P35228 | 6/20 | 0.63 |
| ▸ | NOS1 | P29475 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22670291 | 1.00 | NOS3 (0.63) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL18879382 | 0.81 | NOS3 (0.57) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL18922136 | 0.79 | NOS3 (0.55) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL27144506 | 0.79 | LOXL2 (0.41) | NOS3NOS2LOXL2IGF1RS1PR1 | |
| SCHEMBL14637261 | 0.79 | NOS3 (0.70) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL29432593 | 0.78 | NOS3 (1.00) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL59927 | 0.78 | NOS3 (1.00) | NOS3NOS2NOS1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL13736855 | 0.77 | LOXL2 (0.40) | NOS3NOS2NOS1KDM4ELOXL2 | |
| Bromide SCHEMBL5756062 | 0.76 | NOS3 (0.96) | NOS3NOS2NOS1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL31372470 | 0.76 | NOS3 (0.96) | NOS3NOS2NOS1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |